PGDH19 Detailed Program
| PGDH19 | Population Genetics and Demographic History |
|---|---|
| Mon, 13th May | Coalescent theory - Day #1 |
| 09:30 - 11:00 | Introductions and expectations. Wright-Fisher model and Kingman’s coalescent. |
| 11:00 - 11:30 | Coffee Break |
| 11:30 - 12:30 | Coalescent simulations using ms. |
| 12:30 - 14:00 | Lunch Break |
| 14:00 - 16:00 | Introduction to the R statistical language (Quick Recap). |
| 16:00 - 16:30 | Tea Break |
| 16:30 - 18:00 | Coalescent simulations and tree visualizations using R packages. |
| Tue, 14th May | Demographic Inference in Population Genetics 1 - Day#2 |
| 09:30 - 11:00 | Morning Wrap-up (what have we done so far? The Coalescent with Recombination and the Sequentially Markovian Coalescent. |
| 11:00 - 11:30 | Coffee Break |
| 11:30 - 12:30 | Fast SimCoal and the Site Frequency Spectrum (SFS) 1. |
| 12:30 - 14:00 | Lunch Break |
| 14:00 - 16:00 | Fast SimCoal and the Site Frequency Spectrum (SFS) 2. |
| 16:00 - 16:30 | Tea Break |
| 16:30 - 18:00 | Fast SimCoal and the Site Frequency Spectrum (SFS) 3. |
| Wed, 15th May | Demographic Inference in Population Genetics 2 - Day#3 |
| 09:30 - 11:00 | Morning Wrap-up (what have we done so far?) Population Structure and outlier loci using pcadapt I. |
| 11:00 - 11:30 | Coffee Break |
| 11:30 - 12:30 | Population Structure and outlier loci using pcadapt II. |
| 12:30 - 14:00 | Lunch Break |
| 14:00 - 16:00 | ABC (Approximate Bayesian Computation) in pop genetics and pop genomics I. |
| 16:00 - 16:30 | Tea Break |
| 16:30 - 18:00 | ABC (Approximate Bayesian Computation) in pop genetics and pop genomics II. |
| Thu, 16th May | Influence of population structure on the demographic inference - Day#4 |
| 09:30 - 11:00 | Morning Wrap-up (what have we done so far?) Practicals: Plotting coalescent trees under structured scenarios. |
| 11:00 - 11:30 | Coffee Break |
| 11:30 - 12:30 | Introduction to the PSMC method for reconstructing population size changes based on one diploid genome |
| 12:30 - 14:00 | Lunch Break |
| 14:00 - 16:00 | Practicals: using PSMC for reconstructing demographic history from data simulated with ms. |
| 16:00 - 16:30 | Tea Break |
| 16:30 - 18:00 | Signals of population size changes in structured populations. Introduction of the Inverse Instantaneous Coalescence Rate (IICR). |
| Fri, 17th May | Demographic history with genomic data - Day#5 |
| 09:30 - 11:00 | Morning Wrap-up (what have we done so far? The IICR as a guide to demographic inference and model exclusion/choice (I). |
| 11:00 - 11:30 | Coffee Break |
| 11:30 - 12:30 | The IICR as a guide to demographic inference and model exclusion/choice. (II). |
| 12:30 - 14:00 | Lunch Break |
| 14:00 - 16:00 | Wrap Up on Demographic history and genomic data. |
| 16:00 - 16:30 | Tea Break |
| 16:30 - 18:00 | Final Discussion / Course Wrap Up. |
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